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KMID : 0351619670080020391
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Kyungpook Medical Journal
1967 Volume.8 No. 2 p.391 ~ p.400
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Effects of Testosterone on the Growth of Vaeious Organs in Chick Embryos
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朱剛/Joo, Kang
郭外景/金達洙/朴洋奎/Kim, Dal Soo/Kwak, Oe Kyong/Park, Yang Kyu
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Abstract
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Although many research have been described previously for the various effects of testosterone on the several embryos, most of these study are based on simple weight gain which is not adequate for evaluation of the various organs statistically.
The author intended to determine the effects of testosterone on the weight gain of body weight and various organs of chick embryos. On the 8th and 12th day of incubation, 0.5 mg and 7.5 mg of testosterone were injected into chorioallantoic membrane of each incubate egg of two groups, and each main group were divided into three more small groups such as control, 0.5 mg injected group and 7.5 mg injected group. Between the 12th aAd 18th of incubation day, a daily total or´ 10 treated eggs was broken for weighing the body weights of chick embryos and sip organsbrain, eye ball, heart, lung, liver and k id ne}*.
The effects of doses and difference of injection times on growth were analyzed by the Repeated Two Way Lay out Method, and the determination of the significance in the levels of dif$e-´-rence was made by the Tukey´s Method.
The results are summarized as follows:
1. When injected with testosterone injectable aqueous ;suspension, the chick embryos were observed with significant difference on the growth of organs, between the 8th day group and the 12th day group.
2. In the 8th day group, growth retardation appeared in body weight, brain, eye-ball, lung liver and kidney throughout 7.5mg injected group.
3. Generally, the growth inhibition was found on the 12th day group in comparison with control group.
4. In tine both 8th day group and the 12th day group, were unique in that the growth increasing appeared hearts in 7.5 mg injected group.
5. When injected with 7.5mg testosterone on the 8th da,y, kidney were observed with growth inhibition, but on the other hand, 12th day injected group showed growth promotion.
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